I should wish also that such persons were carefully shewn the eleven pellicles which, like so many small valves, open and shut the four orifices that are in these two cavities, viz., three at the entrance of the hollow vein, where they are disposed in such a manner as by no means to prevent the blood which it contains from flowing into the right ventricle of the heart, and yet exactly to prevent its flowing out; three at the entrance to the arterial vein, which, arranged in a manner exactly the opposite of the former, readily permit the blood contained in this cavity to pass into the lungs, but hinder that contained in the lungs from returning to this cavity; and, in like manner, two others at the mouth of the venous artery, which allow the blood from the lungs to flow into the left cavity of the heart, but preclude its return; and three at the mouth of the great artery, which suffer the blood to flow from the heart, but prevent its reflux.

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René Descartes

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Metropolitan Museum of Art

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Discourse on the Method (Veitch translation)

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Nor do we need to seek any other reason for the number of these pellicles beyond this that the orifice of the venous artery being of an oval shape from the nature of its situation, can be adequately closed with two, whereas the others being round are more conveniently closed with three.

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And that there may be less difficulty in understanding what I am about to say on this subject, I advise those who are not versed in Anatomy, before they commence the perusal of these observations, to take the trouble of getting dissected in their presence the heart of some large animal possessed of lungs, (for this is throughout sufficiently like the human,) and to have shewn to them its two ventricles or cavities: in first place, that in the right side, with which correspond two very ample tubes, viz., the hollow vein, (vena cava,) which is the principal receptacle of the blood, and the trunk of the tree, as it were, of which all the other veins in the body are branches; and the arterial vein, (vena arteriosa,) inappropriately so denominated, since it is in truth only an artery, which, taking its rise in the heart, is divided, after passing out from it, into many branches which presently disperse themselves all over the lungs; in the second place, the cavity in the left side, with which correspond in the same manner two canals in size equal to or larger than the preceding, viz., the venous artery, (arteria venosa,) likewise inappropriately thus designated, because it is simply a vein which comes from the lungs, where it is divided into many branches, interlaced with those of the arterial vein, and those of the tube called the windpipe, through which the air we breathe enters; and the great artery which, issuing from the heart, sends its branches all over the body.