Discourse on the Method, part 5, ¶ 8-9

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René Descartes

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And God blessed them and God sayd vnto them. Growe and multiplye and fyll the erth and subdue it and have domynyon over the fysh of the see and over the foules of the ayre and over all the beastes that move on the erth. Genesis 1:28 TYN

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Discourse on the Method (Veitch translation)

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Is not also the operation which converts the juice of food into blood easily comprehended, when it is considered that it is distilled by passing and repassing through the heart perhaps more than one or two hundred times in a day?

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This receives confirmation from the circumstance, that it is observed of animals destitute of lungs that they have also but one cavity in the heart, and that in children who cannot use them while in the womb, there is a hole through which the blood flows from the hollow vein into the left cavity of the heart, and a tube through which it passes from the arterial vein into the grand artery without passing through the lung.