In conclusion, I am unwilling here to say anything very specific of the progress which I expect to make for the future in the Sciences, or to bind myself to the public by any promise which I am not certain of being able to fulfil; but this only will I say, that I have resolved to devote what time I may still have to live to no other occupation than that of endeavouring to acquire some knowledge of Nature, which shall be of such a kind as to enable us therefrom to deduce rules in Medicine of greater certainty than those at present in use; and that my inclination is so much opposed to all other pursuits, especially to such as cannot be useful to some without being hurtful to others, that if, by any circumstances, I had been constrained to engage in such, I do not believe that I should have been able to succeed.

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René Descartes

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See pp. 9, 72.

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Discourse on the Method (Veitch translation)

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Of this I here make a public declaration, though well aware that it cannot serve to procure for me any consideration in the world, which, however, I do not in the least affect; and I shall always hold myself more obliged to those through whose favour I am permitted to enjoy my retirement without interruption than to any who might offer me the highest earthly preferments.

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And if I write in French, which is the language of my country, in preference to Latin, which is that of my preceptors, it is because I expect that those who make use of their unprejudiced natural Reason will be better judges of my opinions than those who give heed to the writings of the ancients only; and as for those who unite good sense with habits of study, whom alone I desire for judges, they will not, I feel assured, be so partial to Latin as to refuse to listen to my reasonings merely because I expound them in the vulgar Tongue.