- Blaine is a suburban city in Anoka and Ramsey counties in Minnesota, United States. Once a rural town, Blaine’s population has increased significantly in the last 60 years. For several years, Blaine led the Twin Cities metro region in new home construction. The population was 70,222 at the 2020 census. The city is mainly in Anoka County, and is part of the Minneapolis–Saint Paul metropolitan area.