- Dissociatives, colloquially dissos, are a subclass of hallucinogens which distort perception of sight and sound and produce feelings of detachment – dissociation – from the environment and/or self. Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include dissociation, a general decrease in sensory experience, hallucinations, dream-like states or anesthesia. Despite most dissociatives’ main mechanism of action being tied to NMDA receptor antagonism, some of these substances, which are nonselective in action and affect the dopamine and/or opioid systems, may be capable of inducing more direct and repeatable euphoria or symptoms which are more akin to the effects of typical “hard drugs” or common drugs of abuse. This is likely why dissociatives are considered to be addictive with a fair to moderate potential for abuse, unlike psychedelics. Despite some dissociatives, such as phencyclidine (PCP) possessing stimulating properties, most dissociatives seem to have a general depressant effect and can produce sedation, respiratory depression, nausea, disorientation, analgesia, anesthesia, ataxia, cognitive and memory impairment as well as amnesia.
- Children of Men (Wikipedia)
Children of Men is a 2006 dystopian action thriller film directed and co-written by Alfonso Cuarón. The screenplay, based on P. D. James’ 1992 novel The Children of Men, was credited to five writers, with Clive Owen making uncredited contributions. The film is set in 2027 when two decades of human infertility have left society on the brink of collapse. Asylum seekers seek sanctuary in the United Kingdom, where they are subjected to detention and refoulement by the government. Owen plays civil servant Theo Faron, who tries to help refugee Kee (Clare-Hope Ashitey) escape the chaos. Children of Men also stars Julianne Moore, Chiwetel Ejiofor, Pam Ferris, Charlie Hunnam, and Michael Caine.