- Fentanyl is a potent synthetic piperidine opioid primarily used as an analgesic. It is 50 times more potent than heroin and 100 times more potent than morphine; its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. Fentanyl is also used as a sedative. Depending on the method of delivery, fentanyl can be very fast acting and ingesting a relatively small quantity can cause overdose. Fentanyl works by activating μ-opioid receptors. Fentanyl is sold under the brand names Actiq, Duragesic and Sublimaze, among others.
- Peshastin, Washington (Wikipedia)
Peshastin is a small unincorporated community in Chelan County, Washington, United States. The community’s roots are found in the “Peshastin Ditch” dug by pioneers beginning in 1889. This ditch was an important part of the overall irrigation system in the area, delivering water to the orchards on the slopes above Cashmere. The town was first platted in the early 1890s by two brothers, J. Q. Gilbert and A. C. Gilbert. It is also noted on an 1895 map of the area, indicating it was in existence by then.