psilocybin

chemical structure

In the Beginning there was nothing, which exploded. Terry Pratchett, Lords and Ladies

Paul Stamets Stack: Microdosing Psilocybin and Lion’s Mane (microdosinginstitute.com) The Paul Stamets Stack or stacking Lion’s Mane has quickly gained popularity in the microdosing community. Stacking refers to combining various non-psychoactive substances with a psychoactive microdosing substance to increase the benefit related to microdosing. Since renowned mycologist Paul Stamets first mentioned this stacking combination, a large community of biohackers, microdosers and people looking to improve their brain health have adopted Stamets’ (now patented) microdosing stacking method.
Paul Stamets - Mycologist (paulstamets.com)

Psilocybin (Wikipedia) Psilocybin (/ˌsaɪləˈsaɪbɪn/ sy-lə-SY-bin, /ˌsɪl-/) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi. The most potent are members of genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera. Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of lysergic acid diethylamide (LSD), mescaline, and dimethyltryptamine (DMT). In general, the effects include euphoria, visual and mental hallucinations, changes in perception, distorted sense of time, and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks.