Super Mario Bros. 3 (allthetropes.org)
Super Mario Bros. 3 is the third installment in the Super Mario Bros series by Nintendo. The final installment in the trilogy, it featured several new power-ups and features, in addition to a much larger selection of levels, enemies, and so forth (including Bowser’s kids). It was a huge commercial success, rivaling the original Super Mario game. SMB 3 was also the first Mario game to have a specific cartoon Spin-Off, in the form of The Adventures of Super Mario Bros. 3. It also received advance publicity from an otherwise non-notable movie called The Wizard (film).- Substrate (biology) (Wikipedia)
In biology, a substrate is the surface on which an organism (such as a plant, fungus, or animal) lives. A substrate can include biotic or abiotic materials and animals. For example, encrusting algae that lives on a rock (its substrate) can be itself a substrate for an animal that lives on top of the algae. Inert substrates are used as growing support materials in the hydroponic cultivation of plants. In biology substrates are often activated by the nanoscopic process of substrate presentation.