The duke had a mind that ticked like a clock and, like a clock, it regularly went cuckoo.
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Psilocin (Wikipedia)Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance. It is present in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin. Psilocin is a Schedule I drug under the Convention on Psychotropic Substances. Acting on the 5-HT2A receptors, psilocin modulates the production and reuptake of serotonin. The mind-altering effects of psilocin are highly variable and subjective and resemble those of LSD and DMT.
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Terry Pratchett (Wikipedia)Sir Terence David John Pratchett OBE (28 April 1948 – 12 March 2015) was an English humourist, satirist, and author of fantasy novels, especially comical works. He is best known for his Discworld series of 41 novels.